All Hubel group publications
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Louwagie, T., Wagner, M., Li, R., Yu, G., Petersen, A., Hubel, A., "Characterizing cellular membrane partitioning of DMSO using low-temperature Raman spectroscopy", Front. Mol. Biosci., 2023: DOI: doi.org/10.3389/fmolb.2023.1144059
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Joules, A., Burrows, T., Dosa, P.I., Hubel, A., "Characterization of eutectic mixtures of sugars and sugar-alcohols for cryopreservation", J Mol. Liq., 2022: DOI: doi.org/10.1016/j.molliq.2022.120937
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Li, R., Walsh .P, Truong V., Petersen A., Dutton J.R., Hubel A., "Differentiation of Human iPS Cells Into Sensory Neurons Exhibits Developmental Stage-Specific Cryopreservation Challenges", Front. Cell Dev. Biol., 2021: DOI: doi.org/10.3389/fcell.2021.796960
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Hornberger K., Li R., Duarte Ana Rita C, Hubel A., "Natural deep eutectic systems for nature‐inspired cryopreservation of cells", AIChE J. 2020; e17085: DOI: 10.1002/aic.17085
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Pi C.H., Dosa P.I., Hubel A., “Differential evolution for the optimization of the DMSO-free cryoprotectants: influences of control parameters", J Biomech Engr, 142 (7): DOI: 10.1115/1.4045815.
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Li R., Hornberger K., Dutton J.R., Hubel A., “Cryopreservation of human iPS cell aggregates in a DMSO-free solution-an optimization and comparative study”, Front Biotech, DOI: 10.3389/fbioe.2020.00001.
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Pi C.H., Hornberger K., Dosa P.I., Hubel A., “Understanding the freezing responses of T-cells and other subsets of human peripheral blood mononuclear cells using DSMO-free cryoprotectants", Cytotherapy, 22(5): 291-300, 2020. DOI: 10.1016/j.jcyt.2020.01.013.
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Yu G., Li R., Hubel A., “Interfacial interactions of sucrose during cryopreservation detected by Raman spectroscopy”, Langmuir, 35(23): p. 7388-7395, 2019.m DOI: 10.1021/acs.langmuir.8b01616
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Pi C.H., Yu G., Dosa P.I., Hubel A., “Characterizing modes of action and interaction for multicomponent osmolyte solutions on Jurkat cells”, Biotech & Bioengr, 116(3): p. 631-643, 2019. DOI: 10.1002/bit.26880
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Hornberger K, Yu G, McKenna DH, Hubel A, “Cryopreservation of hematopoietic stem cells: emerging cryoprotectants, and technology to improve outcome”, Trans Med Hemotherapy, 4(3): p. 188-196, 2019. DOI: 10.1159/000496068
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Yu G, and Hubel A, “The role of preservation in the variability of regenerative medicine products”, Regen Engr and Trans Med, 5(4): 323-331, 2019, doi.org/10.1007/s40883-019-00110-9
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Li R, Johnson R, Yu G, McKenna DH, Hubel A, “Preservation of cell-based immunotherapies for clinical trials”, Cytotherapy, 21(9): 943-957, 2019.
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Li R, Yu G, Azarin SM, Hubel A, “Freezing responses in DMSO-based cryopreservation of human iPS cells: aggregates versus single cells”, Tissue Engineering: Part C, 24 (5): 289-299, 2018. DOI: 10.1089/ten.tec.2017.0531
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Pi CH, Yu G, Petersen A, Hubel A, “Characterizing the ‘Sweet spot” for the preservation of a T-cell line using osmolytes”, Scientific Reports, 8(1): p. 16223, 2018. DOI: 10.1038/s41598-018-34638-7.
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Pollock K, Budenske JW, McKenna DH, Dosa PI, Hubel A, “Algorithm-driven optimization of cryopreservation protocols”, J Tissue Engr Regen Med, 10: 2806-2815, 2017. DOI: 10.1002/term.2175.
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Pollock K, Samsonraj RM, Dudakovic A, Thaler R, Stumbras A, McKenna DH, Dosa PI van Wijnen AJ, Hubel A, “Improved post-thaw function and epigenetic changes in mesenchymal stromal cells cryopreserved using multicomponent osmolyte solutions”, Stem Cells and Development, 26: 828-842, 2017. DOI: 10.1089/scd.2016.0347
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Yu G, Pollock K, Yap YR, Hubel A, “Characterizing intracellular ice formation of lymphoblasts cryopreserved in different cryoprotectant compositions using low temperature Raman microspectroscopy”, Biophysical J, 112 (12): 2653-2663, 2017. DOI: 10.1089/ten.tec.2016.0284.
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Pollock K, Yu G, Moller-Trane R, Koran M, Dosa PI, McKenna DH, Hubel, A, “Combinations of osmolytes, including monosaccharides, disaccharides and sugar alcohols act in concert during cryopreservation to improve mesenchymal stromal cell survival”, Tissue Engineering: Part C, 22: 999-1006, 2016. DOI: 10.1089/ten.tec.2016.0284.